Ten remarkable facts about making antibody medicines

Ten remarkable facts about making antibody medicines

Xổ số miền nam thứ 7 tuần trướcAntibodies play an important role in our immune systems, defending our bodies from invaders like viruses. By making antibody medicines, we can help fight a variety of diseases. Read on to find out more about the complex processes involved.

A scientist monitoring machinery in the laboratory

1. The Role of Antibodies

Antibodies attach to invaders from outside the body as part of our natural defence to certain illnesses. Today, antibody medicines are made to copy this process to help fight diseases including cancer, rheumatoid arthritis and viruses.

A pill next to a medicine with a more complex structure

2. The Size of an Antibody Medicine

Antibodies are very large, complex proteins made of around 25,000 atoms, whereas medicines like common painkillers may only have around 20 atoms.

A scientist holding up a vial to inspect quality and purity of the substance

3. Making an Antibody Medicine

In our bodies, antibodies are made by a type of white blood cell, which protects the body against foreign invaders. When manufacturing antibody medicines they are also made in living cells.

A checklist

4. Antibody Medicine Manufacturing Time

Making antibody medicines is a very complex process. In order to create a new antibody it takes around 12 months from the first step, when a genetic code is given to cells as an instruction manual to produce the antibody, through to the medicine being ready to distribute to patients (following comprehensive testing).

Four scientists surrounded by laboratory equipment that is growing antibody medicines

5. Antibody Medicine Manufacturing and Testing

Manufacturing antibodies inside living cells is an intricate, multi-step process. It involves constant testing to ensure it is done safely, accurately, and in a completely clean environment.

Illustration of antibody development

6. Identical Cells, Identical Antibodies

The term ‘monoclonal’ antibody means an antibody made from identical living cells (mono = single; clonal = clone). These identical cells produce identical antibodies, which is crucial when making a medicine.

Employees wearing goggles, hair nets and white overalls standing next to production tanks

7. Growing Antibody Medicines

To make enough antibody medicine for patients in need, the cells that are used to grow the antibody are multiplied in production tanks containing trillions of cells.

Food for antibodies going into a tank

8. Feeding an Antibody Medicine

Antibody production tanks contain ‘food’ for the cells growing in them. This food is carefully prepared from as many as 100 different materials.

A woman packaging boxes of vials

9. Safety Precautions and Antibody Medicines

Xổ số miền nam thứ 7 tuần trướcOnce the antibodies have formed correctly, they are separated from the fluid they grew in and other unwanted substances. Then they are packaged and safety tested again. Only then can the medicine be ready.

An illustration of a scale weighing up antibody medicines compared other medicines

10. Advancements in Antibody Manufacturing Technology

30 years ago, it was only possible to produce a few grams of antibodies in one year. Today we can produce over 10 tonnes. We are always striving to improve processes to help deliver medicines to people who need them quickly, but maintaining the highest standards of quality and safety must remain our priority.

Tags: Science, Manufacturing, Biotechnology